Showing posts with label Cardiovascular diseases. Show all posts
Showing posts with label Cardiovascular diseases. Show all posts

Thursday, 18 April 2013

Nuts For Healthy Heart

WHAT ARE NUTS?


Nuts are botanically a type of single-seeded fruit in which the pericarp enclosing the seed is a hard woody shell. In common usage the term is used loosely for any hard, oil rich kernel. Of those commonly eaten, only hazel, filbert and chestnut are strictly nuts. Walnuts, pecans, almonds and coconuts are really drupes. Brazil nuts, pistachios, macadamias, and cashews are really seeds with a hard shell derived from the testa rather than the pericarp.[i]

Image courtesy: radientyounutrion.com

According to the Spanish Food Code, nuts are those fruits the edible part of which has in its composition less than 50% of water. The products of certain trees are called nuts (tree nuts): almonds, hazelnuts, macadamia nuts, walnuts, cashew nuts, pine nuts and pistachios. In this group are also included peanuts and sunflower seeds.[ii]

WHY NUTS ARE SUGGESTED FOR CVDs PATIENTS?


On the basis of Epidemiological evidences, Nutritional, in -vitro studies and clinical trials nuts are considered as cardioprotectant functional food.

EPIDEMIOLOGICAL EVIDENCES


Some of the epidemiological studies are:

·         The Adventis health study
·         The Iowa women’s health study
·         The Nurses’ health study
·         All cause mortality and nut consumption
·         Secondary CHD prevention[iii]

 The epidemiologic studies have reported various endpoints, including fatal CHD, total CHD death, total CHD, and nonfatal myocardial infarct. In conclusion, the results of all the epidemiological studies confirm the cardiovascular protection of nuts. This protection is extended both to men and women of different races and ages, including postmenopausal. In addition, the protection, also, has been described in individuals with normal and with high blood pressure. At the same time, the consumption of nuts is associated with a low mortality rate and an increase in life expectancy without total cardiovascular disease total, which means living for a longer time free of this type of illnesses.

CARDIOPROTECTIVE NUTRIENTS AND DIETARY FACTORS IN NUTS


Image courtesy: es123fr.com
Nuts contain a combination of at least 28 different essential nutrients. Nuts are an excellent source of polyunsaturated and monounsaturated fats – the good fats – which can help manage blood cholesterol. A recent meta analysis found that eating on average 67g of nuts per day reduced total cholesterol by 5%, LDL (bad) cholesterol by 7% and triglycerides by 10%. In addition to being a rich source of several essential vitamins and minerals, mono- and polyunsaturated fatty acids, and fiber, most tree nuts provide an array of phytochemicals that may contribute to the health benefits attributed to this whole food. Although many of these constituents remain to be fully identified and characterized, broad classes include the carotenoids, hydrolyzable tannins, lignans, naphthoquinones, phenolic acids, phytosterols, polyphenols, and tocopherols. These phytochemicals have been shown to possess a range of bioactivity, including antioxidant, antiproliferative, anti-inflammatory, antiviral, and hypocholesterolemic properties. 

Studies have shown that those who eat a handful (30g) of nuts at least five times a week reduce their risk of heart disease by 30–50%.2–5 Nuts rich in monounsaturated fats include macadamias, hazelnuts, cashews, almonds, pistachios and pecans. While walnuts, pine nuts and Brazil nuts are rich in polyunsaturated fats. All nuts contribute fiber to the diet, containing about 8g per 100g on average. Dietary fiber can help manage cholesterol and is essential for a healthy bowel function.[iv]


REFERENCES




[ii] Dr. Rosa SOLĂ€ ALBERICH, Effects of Nuts on cholesterol and cardiovascular diseases.
[iii] Hand book of Nutraceuticals and Functional food; pg 484-497.
[iv] 2012 Nutrient Composition of Tree Nuts, www.nutsforlife.com.au (Accessed on March, 28th 2013)

Wednesday, 27 March 2013

Don't Overlook Beans!

The populations with lower intake of animal protein and higher intake of various beans including soy bean & soy bases foods have found notable low risk of coronary heart disease. Soy protein lowers plasma, total & LDL cholesterol in hypercholesterolemia conditions. It has shown to significantly reduce hepatic cholesterol and increase bile acid excretion. Hydrophobic undigested and high molecular weight undigested fractions of soy protein have been shown to lower cholesterol and bind bile acid even more than soy protein.  Bile acids are acidic steroids synthesis in the live from cholesterol after conjugation with glycine or taurine. The hypothesized possible mechanism by which dietary fiber lowers cholesterol on the binding of bile acid and increasing their fecal excretion. The healthful and cholesterol lowering properties of food fractions by evaluation the vitro bile acid binding between vitro studies showing that cholestyramine binds bile acids and cellulose does not. In vitro binding of bile acid by soy bean, black eye bean, garbanzo and lima bean was determined, using a mixture of bile acids.


 The results indicate that bile acid binding by garbanzo is highest followed by  black eye beans and lima beans at equal and at last soy beans shows their relative health-promoting potential. Incorporation of garbanzo, black eye and lima bean in diets should be encouraged. Data suggest that, of all four kinds of beans tested, bile acid binding may be related to phytochemical i.e. flavanoid, tannin, estrogenic content, anionic, cationic, physical and chemical structure, composition and metabolites produced during digestion or their interaction with active binding sites, or their interaction with active binding sites.

References:
Summary written by Aysha Marium, M.phil Scholar. 
Article: In vitro binding of bile acid by soy bean ( Glycine max ), black eye bean ( vigna unguicilata ) , garbanzo ( cicer arietinum ) and lima bean ( Pharsalus Lunatus )/T.S Kahlon , Q. Shao.
Image courtesy: torontosum.com




Thursday, 21 March 2013

Cardiovascular diseases, Cancer And Bile Acid Binding

In vitro bile acid binding can be used as tool to evaluate cholesterol lowering and cancer risk reduction ability of food. Bile acid are end product of cholesterol metabolism, synthesized in liver and required for fat absorption in gastrointestinal tract. Absorbed fat metabolism leads to cholesterol production in body. Bile acid binding of food prevents their reabsorption and stimulates blood and liver cholesterol conversion into bile acid. Secondary bile acids increase the risk of colorectal cancer. Excretion of bile acid is the major route cholesterol removal from the body. Bile acid binding values determined relative to Cholestrymine ( Bile acid binding, cholesterol lowering drug) binding is a cost effective method for screening foods and food fractions to evaluate their health promoting potential.


Studies suggest that cooked whole grain hard, red winter and hard white winter wheat have significantly higher health promoting potential than their cooked pearled grain counter-parts. It shows red colour associated with whole grain may not necessarily indicate high health benefits.  

Rice and wheat brans have significantly higher Bile acid binding capability than corn and oat bran.Wheat fiber and bran binds bile acid, provides bulk in feces hence prevent colon cancer. Studies show milling improves Bile acid binding. It could be concluded that finer particle size whole grain flour have higher health beneficial effects.

It's been found that process technologies (extruding, shredding, toasting and flaking) and fortification could be used to enhance bile acid binding capability of ready to eat cereals.

"Whole grains and cereals made from whole grains and bran (rice, oat and barley) and legumes, when consumed regularly, can help lower the risk of cardiovascular diseases and certain cancers and improve public health."

Reference:
Health promoting potential of Cereals, Grain fractions, and beans as determined bu their in vitro bile acid binding by T.S Khalon
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